SS-31 (Elamipretide)

About this Product

Scientifically designated as Elamipretide (molecular formula C₃₂H₄₉N₉O₅, 639.8 g/mol), represents a groundbreaking advancement in mitochondrial-targeted therapeutics, engineered by Hazel Szeto and Peter Schiller as the lead compound in their revolutionary peptide series. This synthetic tetrapeptide with the sequence D-Arg-dimethylTyr-Lys-Phe-NH₂ demonstrates unprecedented selectivity for mitochondrial targeting through its unique cardiolipin-binding mechanism, establishing it as a cornerstone research tool for investigating cellular bioenergetics and mitochondrial dysfunction across diverse pathological states. The peptide's alternating aromatic-basic amino acid motif enables it to selectively penetrate cellular and mitochondrial membranes without requiring specific transporters, distinguishing it from conventional antioxidants that distribute non-specifically throughout cellular compartments.